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C. Rob Markus et al.

Evening intake of ALAC increases plasma tryptophan availability and improves morning alertness and brain measures of attention

American Journal of Clinical Nutrition

C. Rob Markus et al. <br>  <br> Evening intake of ALAC increases plasma tryptophan availability and improves morning alertness and brain measures of attention  <br>  <br>  American Journal of Clinical Nutrition

To test whether evening ALAC intake increases the trp/LNAA ratio and improves morning alertness and performance in subjects with sleep disorders. Healthy subjects with or without mild sleep disorder (14+14) participated in this double-blind, placebo-controlled study. Subjects slept in the laboratory for 2 separate nights and ate either a high (alpha-lactalbumin) or low trp diet in the evening. Evening ALAC intake produced a 130% increase in the Trp/LNAA ratio at bedtime and reduced sleepiness and increased alertness the following morning, and, in sleep-disordered patients only, also improved behavioral performance.

Year: 2005

Nationality: The Netherlands

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