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Narek Israeylian et al.

Seretonin as a link between the gut-brain-microbiome axis in autism spectrum disorders

Pharmacological Research

Narek Israeylian et al.  <br> <br> Seretonin as a link between the gut-brain-microbiome axis in autism spectrum disorders  <br>  <br>  Pharmacological Research

As a critical modulator of CNS and ENS development and function, serotonin may be a nexus for the gut-brain axis in ASD.

A mouse model that has been shown to possess brain, behavioral, and gastrointestinal abnormalities that mimic those seen in ASD harbors the most common serotonin transporter (SERT)-based mutation found in children with ASD.

Year: 2018

Nationality: USA

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